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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
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Affinity Data
IC50: 3.60nM
Assay Description:
Inhibition of Matrix metalloproteinase-9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.60nM
Assay Description:
Inhibition of recombinant human MMP9 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
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Affinity Data
IC50: 4.30nM
Assay Description:
Inhibition of Matrix metalloproteinase-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.30nM
Assay Description:
Inhibition of recombinant human MMP3 using (7-methoxycoumarine-4-yl)-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 as substrate by fluorometer ana...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Inhibition of Matrix metalloproteinase-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Inhibition of recombinant human MMP2 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Inhibition of Matrix metalloproteinase-13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Inhibition of recombinant human MMP13 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.50E+3nM
Assay Description:
Inhibition of Matrix metalloproteinase-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096648
(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.50E+3nM
Assay Description:
Inhibition of recombinant human MMP1 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI