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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant human MMP9 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of recombinant human MMP3 using (7-methoxycoumarine-4-yl)-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 as substrate by fluorometer ana...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human MMP2 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase 3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  67nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  67nMAssay Description:Inhibition of recombinant human MMP13 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096648(2-[2-(4'-Chloro-biphenyl-4-yl)-ethoxymethyl]-N-hyd...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant human MMP1 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed