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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP-2 (unknown origin) catalytic activity using Ac-PLG-[2-mercapto-4-methylpentanoyl]-LG-OC2H5 as substrate and measured upto 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of MMP-12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase 3(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50: <5nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of MMP-9 (unknown origin) catalytic activity using Ac-PLG-[2-mercapto-4-methylpentanoyl]-LG-OC2H5 as substrate and measured upto 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50:  50nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStromelysin-2(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50:  181nMAssay Description:Inhibition of MMP-10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMatrilysin(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50: >500nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50: >500nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50:  556nMAssay Description:Inhibition of MMP-14 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592904(CHEMBL5182668)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed