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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
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Affinity Data
IC50: 0.260nM
Assay Description:
Inhibition of matrix metalloprotease-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.260nM
Assay Description:
Inhibition of human recombinant MMP2 by colorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.300nM
Assay Description:
Inhibition of human recombinant MMP2 by colorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
Assay Description:
Inhibition of matrix metalloprotease-8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.5nM
Assay Description:
Inhibitory activity against matrix metalloprotease-13 (MMP-13)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40nM
Assay Description:
Inhibition of matrix metalloprotease-9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.30nM
Assay Description:
Inhibitory activity against matrix metalloprotease-13 (MMP-13)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20nM
Assay Description:
Inhibition of matrix metalloprotease-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Inhibitory activity against human matrix metalloprotease-1 (MMP-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148208
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibitory activity against human matrix metalloprotease-1 (MMP-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI