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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
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Affinity Data
IC50: 0.240nM
Assay Description:
Inhibition of matrix metalloprotease-12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
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Affinity Data
IC50: 0.75nM
Assay Description:
Inhibitory activity against matrix metalloprotease-13 (MMP-13)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
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Affinity Data
IC50: 1.40nM
Assay Description:
Inhibition of matrix metalloprotease-8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Jadavpur University
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
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Copy InChI
Affinity Data
IC50: 1.60nM
Assay Description:
Inhibition of human recombinant MMP2 by colorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Jadavpur University
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60nM
Assay Description:
Inhibition of human recombinant MMP2 by colorimetric analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Jadavpur University
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60nM
Assay Description:
Inhibition of matrix metalloprotease-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.40nM
Assay Description:
Inhibition of matrix metalloprotease-14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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CHEMBL
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In Depth
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Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
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Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of matrix metalloprotease-9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of matrix metalloprotease-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148216
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 420nM
Assay Description:
Inhibitory activity against human matrix metalloprotease-1 (MMP-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI