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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  0.75nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant MMP2 by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  16nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148216(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Affinity DataIC50:  420nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed