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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM11547
(2-[2-(1,1-biphenyl-4-yl)ethyl]-N-hydroxyisothiazol...)
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Affinity Data
Ki: 433nM
Assay Description:
The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM11547
(2-[2-(1,1-biphenyl-4-yl)ethyl]-N-hydroxyisothiazol...)
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Copy InChI
Affinity Data
Ki: 702nM
Assay Description:
The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM11547
(2-[2-(1,1-biphenyl-4-yl)ethyl]-N-hydroxyisothiazol...)
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Copy InChI
Affinity Data
Ki: 1.06E+3nM
Assay Description:
The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Bristol-Myers Squibb
Ligand
BDBM11547
(2-[2-(1,1-biphenyl-4-yl)ethyl]-N-hydroxyisothiazol...)
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Copy InChI
Affinity Data
Ki: >4.95E+3nM ΔG°: >-30.3kJ/mole
pH: 7.5 T: 2°C
Assay Description:
The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI