Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11545(2-(1,1-biphenyl-4-yl)-N-hydroxyisothiazolidine-3-c...)
Affinity DataKi:  667nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11545(2-(1,1-biphenyl-4-yl)-N-hydroxyisothiazolidine-3-c...)
Affinity DataKi:  904nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11545(2-(1,1-biphenyl-4-yl)-N-hydroxyisothiazolidine-3-c...)
Affinity DataKi: >2.13E+3nMAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM11545(2-(1,1-biphenyl-4-yl)-N-hydroxyisothiazolidine-3-c...)
Affinity DataKi: >4.95E+3nM ΔG°: >-30.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed