Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50: >10nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  47nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  49nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  57nMAssay Description:In vitro inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  655nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibition of Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataKd:  100nMAssay Description:Binding affinity to stromelysin-1 catalytic domainMore data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096645(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Affinity DataKd:  110nMAssay Description:Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetryMore data for this Ligand-Target Pair