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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Interstitial collagenase
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
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Affinity Data
IC50: >10nM
Assay Description:
Inhibition of Matrix metalloproteinase-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
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Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
Inhibition of Matrix Metalloprotease-3 (MMP-3)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
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Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
In vitro inhibition of Matrix metalloproteinase-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Inhibition of Matrix metalloproteinase-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 49nM
Assay Description:
Inhibition of Matrix metalloproteinase-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 57nM
Assay Description:
In vitro inhibition of Matrix metalloproteinase-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 64nM
Assay Description:
Inhibition of Matrix metalloproteinase-13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 655nM
Assay Description:
Inhibition of Matrix metalloproteinase-9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Institut De Recherches Servier
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.30E+3nM
Assay Description:
In vitro inhibition of Matrix metalloproteinase-1.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 100nM
Assay Description:
Binding affinity to stromelysin-1 catalytic domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50096645
(3-(4'-Cyano-biphenyl-4-yloxy)-N-hydroxy-propionami...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 110nM
Assay Description:
Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI