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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Peptide deformylase
(Escherichia coli (strain K12))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50100095
(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
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Affinity Data
IC50: 310nM
Assay Description:
Inhibition of the isolated native E. coli peptide deformylase (PDF)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50100095
(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
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Affinity Data
IC50: 460nM
Assay Description:
Inhibition of Collagenase-3, matrix metalloptroteinase-13 (MMP-13).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Endothelin-converting enzyme 1
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50100095
(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition against endothelin-converting enzyme.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50100095
(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
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Affinity Data
IC50: 9.00E+4nM
Assay Description:
Inhibition against angiotensin I converting enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50100095
(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human macrophage elastase, matrix metalloproteinase-12 (MMP-12).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neprilysin
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50100095
(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition against neutral endopeptidase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI