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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Macrophage metalloelastase
(Homo sapiens (Human))
University Of Florence
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
Ki: 2nM
Assay Description:
Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
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Target
Matrilysin
(Homo sapiens (Human))
University Of Florence
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
Ki: 5.00E+3nM
Assay Description:
Inhibition of MMP7 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of MMP2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 2.40nM
Assay Description:
Inhibition of MMP13-mediated collagen degradation by SDS-PAGE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 2.80nM
Assay Description:
Inhibition of MMP13-mediated collagen degradation by SDS-PAGE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 7nM
Assay Description:
Inhibition of MMP8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 34nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
Assay Description:
Inhibition of MMP9 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 70nM
Assay Description:
Inhibition of human recombinant MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
Assay Description:
Inhibition of human recombinant MMP14 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 320nM
Assay Description:
Inhibition of MMP3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 610nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 610nM
Assay Description:
Inhibition of MMP1 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 970nM
Assay Description:
Inhibition of MMP1-mediated collagen degradation by SDS-PAGE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of human recombinant ADAM17 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Meprin A subunit beta
(Homo sapiens)
Fraunhofer Institute For Cell Therapy and Immunology Izi
Curated by
ChEMBL
Ligand
BDBM50294120
(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)
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Affinity Data
IC50: 3.85E+3nM
Assay Description:
Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI