Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126603(4-[(biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126603(4-[(biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]...)
Affinity DataIC50:  124nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126603(4-[(biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase 9 (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50126603(4-[(biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]...)
Affinity DataIC50:  4.17E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50126603(4-[(biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase 1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed