Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50291561(CHEMBL10251 | {1-[(S)-2-Biphenyl-4-yl-1-(1H-tetraz...)Copy SMILESCopy InChI

Affinity DataIC50:  4.80nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50291561(CHEMBL10251 | {1-[(S)-2-Biphenyl-4-yl-1-(1H-tetraz...)Copy SMILESCopy InChI

Affinity DataIC50:  17nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI