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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Endothelin-converting enzyme 1
(Homo sapiens (Human))
Novartis Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50064097
(CHEMBL37456 | {[(S)-4-(2,4-Difluoro-phenyl)-1-(2-p...)
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Affinity Data
IC50: 310nM
Assay Description:
Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neprilysin
(Homo sapiens (Human))
Novartis Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50064097
(CHEMBL37456 | {[(S)-4-(2,4-Difluoro-phenyl)-1-(2-p...)
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Copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibitory activity against neutral endopeptidase (NEP).
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI