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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50256157
(CHEMBL481894 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
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Affinity Data
IC50: 350nM
Assay Description:
Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate reader
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50256157
(CHEMBL481894 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 350nM
Assay Description:
Inhibition of ADAMTS5 by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50256157
(CHEMBL481894 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
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Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of ADAMTS4 by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50256157
(CHEMBL481894 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate reader
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50256157
(CHEMBL481894 | N-((5-chloro-8-hydroxyquinolin-7-yl...)
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Copy InChI
Affinity Data
IC50: >6.70E+4nM
Assay Description:
Inhibition of MMP13 by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI