Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 80 hits in this display
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Ki: 110nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Ki: 2.65E+3nMAssay Description:Inhibition of transmembrane tumor-associated human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Ki: 2.71E+3nMAssay Description:Inhibition of transmembrane tumor-associated human carbonic anhydrase 9 preincubated for 12 hrs by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Ki: 8.96E+3nMAssay Description:Inhibition of transmembrane tumor-associated human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Ki: 9.07E+3nMAssay Description:Inhibition of transmembrane tumor-associated human carbonic anhydrase 12 preincubated for 12 hrs by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 570nMAssay Description:Inhibition of CYP1A2 (unknown origin)-mediated demethylation of resorufin methyl ether after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 670nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 1.29E+3nMAssay Description:Inhibition of CYP1A1 (unknown origin)-mediated deethylation of resorufin ethyl ether after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Integrase(Human immunodeficiency virus 1)South China Normal University
Curated by ChEMBL
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 6.00E+3nMpH: 7.0 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 7.10E+3nMpH: 7.0 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 9.00E+3nMAssay Description:Inhibition of human recombinant CK2 expressed in Escherichia coli using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Integrase(Human immunodeficiency virus 1)South China Normal University
Curated by ChEMBL
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Integrase(Human immunodeficiency virus 1)South China Normal University
Curated by ChEMBL
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: >2.50E+4nMAssay Description:Inhibition of CYP2A6 (unknown origin)-mediated coumarin 7-hydroxylation after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: >2.50E+4nMAssay Description:Inhibition of CYP2B1 (unknown origin)-mediated depentylation of resorufin pentyl ether after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 3.34E+4nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 3.99E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Neuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)Universidad De Buenos Aires
Curated by ChEMBL
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Neuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)Universidad De Buenos Aires
Curated by ChEMBL
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 5.29E+4nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 3.02E+5nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease-mediated ammonia production preincubated for 1.5 hrs by indophenol methodMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: 8.90E+5nMAssay Description:Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assayMore data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
IC50: >1.96E+6nMAssay Description:In vitro antibacterial activity was determined as inhibitory concentration causing 50% DNA-gyrase supercoiling inhibition (SCI)More data for this Ligand-Target Pair
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)
Displayed 1 to 50 (of 80 total ) | Next | Last >>