Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL

LigandBDBM50347708(CHEMBL1802462)Copy SMILESCopy InChI

Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of CARM1-mediated methylation of PABP1 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionineMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL

LigandBDBM50347708(CHEMBL1802462)Copy SMILESCopy InChI

Affinity DataIC50: >6.00E+5nMAssay Description:Inhibition of SET7-mediated methylation of histone H3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionineMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL

LigandBDBM50347708(CHEMBL1802462)Copy SMILESCopy InChI

Affinity DataIC50: >6.67E+5nMAssay Description:Inhibition of PRMT1-mediated methylation of NPL3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionineMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI