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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataKi:  2.30nMAssay Description:Competitive inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using ATP as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataIC50:  14nMAssay Description:Inhibition of DYRK1A (unknown origin) using woodtide as substrate after 10 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataIC50:  23nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataIC50:  43nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataIC50:  166nMAssay Description:Inhibition of DYRK2 (unknown origin) using woodtide as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Qimr Berghofer Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataEC50:  4.80E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed