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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Yonsei University
Curated by
ChEMBL
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of DYRK1B (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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PC sid
In Depth
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Article
PubMed
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Target
Dual specificity protein kinase CLK4
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 4.70nM
Assay Description:
Inhibition of recombinant human CLK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Yonsei University
Curated by
ChEMBL
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
Assay Description:
Inhibition of DYRK1A (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Yonsei University
Curated by
ChEMBL
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.90nM
Assay Description:
Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Yonsei University
Curated by
ChEMBL
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.30nM
Assay Description:
Inhibition of recombinant human DYRK1A expressed in Escherichia coli using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of recombinant human CLK1 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Yonsei University
Curated by
ChEMBL
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of recombinant human DYRK1A expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 14nM
Assay Description:
Inhibition of recombinant human CLK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Yonsei University
Curated by
ChEMBL
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 4
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 27nM
Assay Description:
Inhibition of recombinant human DYRK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scint...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 33nM
Assay Description:
Inhibition of recombinant human DYRK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scint...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha/beta
(Mus musculus (mouse))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 38nM
Assay Description:
Inhibition of recombinant human CDK5/p25 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric sc...
More data for this Ligand-Target Pair
Target Info
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 38nM
Assay Description:
Inhibition of recombinant human CLK1 expressed in Sf9 insect cells using myelin basic protein as substrate incubated for 110 mins in presence of ATP ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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PubMed
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Target
Casein kinase I isoform epsilon
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 39nM
Assay Description:
Inhibition of recombinant human CK1epsilon expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 3
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 72nM
Assay Description:
Inhibition of recombinant human DYRK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scint...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
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Affinity Data
IC50: 159nM
Assay Description:
Inhibition of recombinant human GSK-3beta expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric s...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK3
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
IC50: 207nM
Assay Description:
Inhibition of recombinant human CLK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
Kd: 260nM
Assay Description:
Binding affinity to human GSK-3beta assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Yonsei University
Curated by
ChEMBL
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.5nM
Assay Description:
Binding affinity to human DYRK1A assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
TBA
Ligand
BDBM50571338
(CHEMBL4873449)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.30nM
Assay Description:
Binding affinity to human CLK1 assessed as equilibrium dissociation constant measured upto 240 min by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI