Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL

LigandBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)Copy SMILESCopy InChI

Affinity DataIC50:  30nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEstrogen receptor(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL

LigandBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+3nMAssay Description:Agonist activity at ER by reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAndrogen receptor(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL

LigandBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)Copy SMILESCopy InChI

Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at AR by reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI