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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM26659
(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
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Affinity Data
IC50: 280nM
Assay Description:
Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assay
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM26659
(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
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Affinity Data
IC50: 620nM
Assay Description:
Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...
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Target Info
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
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MMDB
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Loma Linda University
Ligand
BDBM26659
(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
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Affinity Data
IC50: 4.52E+3nM
pH: 7.0 T: 2°C
Assay Description:
The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Loma Linda University
Ligand
BDBM26659
(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
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Affinity Data
IC50: 4.57E+3nM
Assay Description:
Inhibition of PIM1 kinase
Checked by Author
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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MMDB
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In Depth
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Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM26659
(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
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Affinity Data
IC50: 9.50E+3nM
Assay Description:
Inhibition of human recombinant ARTD1 by fluorescence assay
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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MMDB
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In Depth
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM26659
(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
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Affinity Data
IC50: 3.93E+4nM
Assay Description:
Inhibition of p56 lck
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
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MMDB
PC cid
PC sid
PDB
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In Depth
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Article
PubMed
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