Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50:  1.60E+3nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50:  4.63E+3nMAssay Description:Reduction of recombinant ECE2 (unknown origin) activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50: >1.00E+5nMpH: 5.5Assay Description:Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed