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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
EEF1AKMT4-ECE2 readthrough transcript protein
(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai
Ligand
BDBM50271179
(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
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Affinity Data
IC50: 1.60E+3nM
pH: 5.5
Assay Description:
Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
EEF1AKMT4-ECE2 readthrough transcript protein
(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai
Ligand
BDBM50271179
(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
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Copy InChI
Affinity Data
IC50: 4.63E+3nM
Assay Description:
Reduction of recombinant ECE2 (unknown origin) activity measured by McaBk2 fluorescent substrate hydrolysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Endothelin-converting enzyme 1
(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai
Ligand
BDBM50271179
(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
pH: 7.4
Assay Description:
Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Endothelin-converting enzyme 1
(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai
Ligand
BDBM50271179
(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
pH: 5.5
Assay Description:
Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI