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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kJ/mol
)
Found
10
hits in this display
Target
Prostaglandin G/H synthase 1
(Homo sapiens (Human))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of Mitogen activated protein kinase kinase 1 (MKK1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
University Of Utah
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
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Affinity Data
IC50: 2.80E+3nM
Assay Description:
Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Dual specificity mitogen-activated protein kinase kinase 2
(Rattus norvegicus)
University Of Gothenburg
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
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Affinity Data
IC50: 4.20E+3nM
Assay Description:
Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Ligand Info
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Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
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Affinity Data
IC50: 6.20E+3nM
Assay Description:
Inhibition of Photinus pyralis luciferase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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CHEMBL
MCE
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PC sid
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In Depth
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Article
PubMed
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Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.40E+3nM
Assay Description:
Inhibition of Photinus pyralis luciferase by PK-Light assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of MEK1 phosphorylation by activated human recombinant Raf
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of Photinus pyralis luciferase by Easy lite assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.00E+4nM
Assay Description:
Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Luciferin 4-monooxygenase
(Photinus pyralis)
National Human Genome Research Institute
Curated by
ChEMBL
Ligand
BDBM50108771
(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI