Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Dihydrofolate reductase
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM18050
(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 35nM
Assay Description:
Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Dihydrofolate reductase
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50016341
(2-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 82nM
Assay Description:
Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dihydrofolate reductase
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50016342
(2-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dihydrofolate reductase
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50016343
(2-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 310nM
Assay Description:
Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dihydrofolate reductase
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50016339
(2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 540nM
Assay Description:
Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dihydrofolate reductase
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50016340
(2-[4-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 840nM
Assay Description:
Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI