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Found 6 Enz. Inhib. hit(s) with Target = 'Alpha-ketoglutarate-dependent dioxygenase AlkB'
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))TBA
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of Escherichia coli AlkB DNA repair activity using 1-methyladenine with GC-1meA-AGGTCCCGTAGTGCG sequence as substrate by FDH coupled assayMore data for this Ligand-Target Pair
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TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))TBA
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of Escherichia coli AlkB by HPLC analysisMore data for this Ligand-Target Pair
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TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))TBA
LigandPNGBDBM50417864(CHEMBL5286796)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of Escherichia coli AlkB-mediated demethylation using 40-mer single N3-meC containing ssDNA as substrate preincubated for 1 hr followed by...More data for this Ligand-Target Pair
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TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))TBA
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of Escherichia coli AlkB using 15-mer m1A-ssDNA as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))TBA
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  1.08E+5nMAssay Description:Inhibition of Escherichia coli AlkB using 15-mer m1A-ssDNA as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase AlkB(Escherichia coli (strain K12))TBA
LigandPNGBDBM50416550(CHEMBL5274121)
Affinity DataIC50:  1.69E+5nMAssay Description:Inhibition of Escherichia coli AlkB using 15-mer m1A-ssDNA as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed