Report error Found 62 Enz. Inhib. hit(s) with Target = 'GTPase HRas'
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity to HRAS (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HRAS (unknown origin) farnesylationMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human H-rasMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of HRAS (unknown origin) transfected in BALB/c nude mouse incubated for 3 days measured by immunoblot analysisMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of [35S]methionine labelled HRAS in rat Rat1 cells by immunoprecipitation analysisMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) productsMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human recombinant p21RAS by GDPX assayMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Ha-ras polymerase-chain reaction productMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.43E+4nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GST-tagged HRAS (1 to 166 residues) (unknown origin) assessed as inhibition of mSOS1 mediated nucleotide exchange by [35S]GTPgammaS bas...More data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
TargetGTPase HRas(Human)
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Massachusetts College of Pharmacy and Health Sciences University
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair