Affinity DataEC50: 0.0800nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 cells coexpressed with human MD2/CD14 assessed as activation of NFkappaB signaling after 20 to 24 ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 cells coexpressed with human MD2/CD14 assessed as activation of NFkappaB signaling after 20 to 24 ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.780nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 1.32nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 1.39nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 3.95nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 4.99nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 10.2nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 13.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 15.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 19.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 cells coexpressed with human MD2/CD14 assessed as activation of NFkappaB signaling after 20 to 24 ...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 64nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 152nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Affinity DataEC50: 390nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 430nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 920nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.12E+3nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.27E+3nMAssay Description:Antagonist activity at TLR4 (unknown origin) expressed in human AD293 cells assessed as inhibition of LPS/ATP-stimulated TLR4/NF-kB signaling pathway...More data for this Ligand-Target Pair
Affinity DataEC50: 3.27E+3nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair