TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Human)
Biohaven Pharmaceuticals
Curated by ChEMBL
Biohaven Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human CLR/RAMP1 by cAMP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0110nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0170nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0190nMAssay Description:Antagonist activity at human CGRP receptor expressed in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0220nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in mouse E10 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0260nMAssay Description:Antagonist activity at human CGRP receptor expressed in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Human)
Biohaven Pharmaceuticals
Curated by ChEMBL
Biohaven Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human CLR/RAMP1More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Antagonist activity against human CGRP receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0320nMAssay Description:Displacement of [125I]hCGRPa from human recombinant CGRP receptor expressed in CHO cells measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair