Affinity DataEC50: 1.60nMAssay Description:Negative logarithm of the molar concentration for agonist activity at mu receptor was determined in guinea pig ileumMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute Of Neuroscienc
Curated by ChEMBL
National Institute Of Neuroscienc
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Antagonist activity at human recombinant mu opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dermorphin-induced...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute Of Neuroscienc
Curated by ChEMBL
National Institute Of Neuroscienc
Curated by ChEMBL
Affinity DataEC50: 81nMAssay Description:Agonist activity at MOP (unknown origin) expressed in SH-SY5Y cell membranes co-expressing beta-arrestin2-RGFP protein assessed as induction of beta-...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute Of Neuroscienc
Curated by ChEMBL
National Institute Of Neuroscienc
Curated by ChEMBL
Affinity DataEC50: 129nMAssay Description:Agonist activity at MOP (unknown origin) expressed in SH-SY5Y cell membranes co-expressing Gbeta1-RGFP protein assessed as induction of G protein act...More data for this Ligand-Target Pair