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TargetBeta-lactamase TEM(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)
Affinity DataIC50:  0.200nMpH: 7.0 T: 37°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBeta-lactamase SHV-1(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)
Affinity DataIC50:  0.400nMpH: 7.0 T: 37°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBeta-lactamase SHV-1(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)
Affinity DataIC50:  0.800nMpH: 7.0 T: 37°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBeta-lactamase TEM(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)
Affinity DataIC50:  1.70nMpH: 7.0 T: 37°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBeta-lactamase(Escherichia coli (strain K12))
Nabriva Therapeutics

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)
Affinity DataIC50:  285nMpH: 7.0 T: 37°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBeta-lactamase(Escherichia coli (strain K12))
Nabriva Therapeutics

US Patent
LigandPNGBDBM178163(US9120808, Example 41 | US9120808, Example 42)
Affinity DataIC50:  385nMpH: 7.0 T: 37°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent