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Compile Data Set for Download or QSAR
maximum 50k data
Found
1
of ic50 for monomerid = 223200
Target
E3 ubiquitin-protein ligase Mdm2 [17-125]
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM223200
(3-(6-{[(1r)-1- cyclobutylethyl]amino}- 7-[(trans-4...)
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Affinity Data
IC50: 0.626nM
T: 2°C
Assay Description:
An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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