Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for monomerid = 241949
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  5.40E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human topo2alpha by plasmid relaxation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human topoisomerase 2alpha expressed in baculovirus-infected insect cells assessed as reduction in pBR322 supercoiled DNA relaxation af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  2.74E+5nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  2.74E+5nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed