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Found 3 of ic50 for monomerid = 372743
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM372743(6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(4-meth...)
Affinity DataIC50:  0.793nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM372743(6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(4-meth...)
Affinity DataIC50:  4.86nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin D(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM372743(6-((Z)-2-(3-((1S,5S,6S)-3-amino-5-methyl-1-(4-meth...)
Affinity DataIC50:  9.39E+4nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CatD is 0.05M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent