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Found 4 of ic50 for monomerid = 409560
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM409560(2-[6-(5-Chloro-4-methyl-2-thienyl)pyrrolo[3,2-b]py...)
Affinity DataIC50:  21nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2B expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409560(2-[6-(5-Chloro-4-methyl-2-thienyl)pyrrolo[3,2-b]py...)
Affinity DataIC50:  79.4nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM409560(2-[6-(5-Chloro-4-methyl-2-thienyl)pyrrolo[3,2-b]py...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM409560(2-[6-(5-Chloro-4-methyl-2-thienyl)pyrrolo[3,2-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from recombinant human ERG expressed in HEK293 cell membranes measured after 80 mins by TopCount scintillation analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed