TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.538nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Antagonist activity at mouse brain homogenate MOPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at guinea pig ileum MOPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced contractionsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21nMAssay Description:In vitro inhibitory activity against electrically evoked contractions of guinea pig ileum (GPI)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro opioid inhibitory activity against in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of opioid receptor mu in guinea pig ileum (GPI)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Agonist activity for Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Functional bioactivity against mu opioid receptor in guinea-pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Binding affinity to Mu-type opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Evaluated for its affinity towards Opioid receptor mu 1 in rat forebrain by displacing the radioligand [3H]-sufentanil.More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Agonist activity at Mu-type opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]- DAGO from opioid receptor mu in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in guinea pig ileum (Opioid receptor mu 1); inhibitory concentration ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Evaluated for the inhibition of [3H]DAGO binding to mu-receptor of guinea pig brainMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:The compound was tested for binding affinity towards [3H]DAMGO, in rat Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 15.2nMAssay Description:Functional bioactivity against delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 16.5nMAssay Description:In vitro inhibitory activity against electrically evoked contractions of in mouse vas deferens (MVD)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at mouse vas deferns MOPMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Agonist activity at delta-type opioid receptor in mouse vas deferens assessed as inhibition of electrically stimulated contractionsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:In vitro opioid receptor delta mediated mouse vas deferens (MVD) assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Antagonist activity at mouse brain homogenate DOPMore data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Evaluated for the inhibition of [3H]DADLE binding to Opioid receptor delta 1 of guinea pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: 294nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Agonist activity at delta-type opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Evaluated for its affinity towards Opioid receptor delta 1 in rat fore brain by displacing the radioligand [3H]-DPDPE.More data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Binding affinity to delta-type opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Displacement of [3H]- DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Affinity for rat Tachykinin receptor 1 determined in displacement screening by using radioligand 3,4-[3H]-(L-Pro e2) SP.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at mouse brain homogenate KOPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Evaluated for the inhibition of [3H]EKC binding to Opioid receptor kappa 1 of guinea pig brainMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOC from human ORL1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair