Compile Data Set for Download or QSAR
maximum 50k data
Found 13 of ic50 for monomerid = 50095495
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  1.50E+3nMpH: 5.5Assay Description:Effect of 10 mM of GSH on the inhibitory activity of compound against Cathepsin K, at pH 5.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human recombinant cathepsin L after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  1.63E+3nMpH: 5.5Assay Description:Inhibition of Cathepsin K at pH 5.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  2.30E+3nMpH: 7.0Assay Description:Inhibition of Cathepsin K at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  3.40E+3nMpH: 7.0Assay Description:Effect of 10 mM of GSH on the inhibitory activity against Cathepsin K, at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of human recombinant cathepsin K after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of human recombinant cathepsin S after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of human recombinant cathepsin C after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095495(CHEMBL262697 | Pyrrolidine-1-carbonitrile)
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of human recombinant cathepsin B after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed