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Found 10 of ic50 for monomerid = 50112180
TargetNeuromedin-K receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  6.30nMAssay Description:Antagonist activity against human recombinant NK3R expressed in CHO cells by aequorin functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  7nMAssay Description:Chinese Hamster Ovary recombinant cells expressing the human NK-3 receptor and a construct that encodes the photoprotein apoaequorin were used for th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuromedin-K receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  7nMAssay Description:Changes in intracellular calcium levels are a recognized indicator of G protein-coupled receptor activity. The efficacy of compounds of the invention...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuromedin-K receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  7nMAssay Description:Changes in intracellular calcium levels are a recognized indicator of G protein-coupled receptor activity. The efficacy of compounds of the invention...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50112180(CHEMBL3608688 | US10030025, Compound 41 | US108367...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed