Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ic50 for monomerid = 50126041
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human FTase-catalyzed incorporation of [3H]FPP into recombinant Ras CVIMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of [3H]-FPP incorporation into recombinant Ras CVIM by human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of [3H]-GGPP incorporation into C-terminus of K-Ras by human Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human GGTase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide of C-terminal of human K-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human GGTase-catalyzed incorporation of [3H]GGPP into biotinylated peptide of C-terminal of human K-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed