Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human EGFR expressed in baculovirus by fluorescence based assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of His-tagged human recombinant Her2 (676 to 1255 residues) expressed in baculovirus by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 287nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair