Report error Found 45 of ic50 for monomerid = 50169959
Affinity DataIC50: 30nMAssay Description:Inhibition of PIM3 in the presence of 5uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of GSK3-beta in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of c-Jun N-Terminal kinase 3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
TargetMitogen-activated protein kinase 10(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human JNK3Checked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of PIM1 in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rat)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human JNK1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of c-Jun N-Terminal kinase 1More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against c-Jun N-Terminal kinase 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
TargetMitogen-activated protein kinase 9(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human JNK2Checked by AuthorMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of DYRK2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of c-SRC tyrosine kinaseMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of RAF proto-oncogene serine/threonine protein kinaseMore data for this Ligand-Target Pair
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of JNK1 in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of MAP kinase p38 alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of JNK2 in the presence of 20uM ATPMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mitogen activated protein kinase kinase 1 (MEK1)More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against PDK 1More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mitogen activated protein kinase kinase 7 betaMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AKT kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BLK; Range is 5-10More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAP kinase-activated protein kinase 2More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of protein kinase ROCK2; Range is 5-10More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1/beta-2(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CHK1 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of protein kinase C alphaMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-5(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MSK-1 kinase; Range is 5-10More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERK1 kinaseMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IKKB kinaseMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 5(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of protein kinase PRAKMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 6(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Mitogen activated protein kinase 6; Range is 5-10More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Ribosomal S6 kinase 2; Range is 5-10More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SGK; Range is 5-10More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Mitogen activated protein kinase kinase 4More data for this Ligand-Target Pair