Compile Data Set for Download or QSAR
maximum 50k data
Found 10 of ic50 for monomerid = 50193810
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50:  1nMAssay Description:Inhibition of human FAK expressed in baculovirus after 30 mins using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human ALK expressed in baculovirus using recombinant GST PLC-gamma as substrate assessed as phosphorylation of the substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50:  50nMAssay Description:Inhibition of NPM-ALK phosphorylation in human SUP-M2 cells after 2 to 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50:  81nMAssay Description:Inhibition of recombinant human INSR expressed in baculovirus using ATP as substrate after 15 mins by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50: >5.60E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate in presence of NADPH by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50: >5.60E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate in presence of NADPH by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50: >5.60E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate in presence of NADPH by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50: >5.60E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate in presence of NADPH by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50: >5.60E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone/midazolam as substrate in presence of NADPH by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193810(CHEMBL3972653)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed