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Found 4 of ic50 for monomerid = 50203224
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50203224(CHEMBL3953069 | US11530198, Example 1)
Affinity DataIC50:  13.8nMAssay Description:TBDMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50203224(CHEMBL3953069 | US11530198, Example 1)
Affinity DataIC50:  17nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR expressed in Escherichia coli BL21 preincubated for 15 mins followed by addition of DHF as substrate and NADP...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50203224(CHEMBL3953069 | US11530198, Example 1)
Affinity DataIC50:  75.9nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50203224(CHEMBL3953069 | US11530198, Example 1)
Affinity DataIC50:  92nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli preincubated for 15 mins followed by addition of DHF as substrate and NADPH measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed