Found 7 of ic50 for monomerid = 50217552 TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Institut De Recherche Jouveinal-Parke Davis
Curated by ChEMBL
Institut De Recherche Jouveinal-Parke Davis
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Institut De Recherche Jouveinal-Parke Davis
Curated by ChEMBL
Institut De Recherche Jouveinal-Parke Davis
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Institut De Recherche Jouveinal-Parke Davis
Curated by ChEMBL
Institut De Recherche Jouveinal-Parke Davis
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Displacement of [3H]rolipram from rat brain membrane suspensionsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 3 (PDE3) isolated from the dog aortaMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C/cGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1/5 isozyme (PDE1/5) mixture isolated from the guinea pig trachea.More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP.More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C/cGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [...More data for this Ligand-Target Pair
