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Found 6 of ic50 for monomerid = 50262653
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50262653(2,4-Diamino-5-propyl-6-(2'-naphthylsulfanyl)-7H-py...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed