Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 50325818
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325818(2-(2'-(trifluoromethoxy)biphenyl-3-yl)thiazole-4-c...)
Affinity DataIC50:  50nMAssay Description:Blockade of human Nav1.7 by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325818(2-(2'-(trifluoromethoxy)biphenyl-3-yl)thiazole-4-c...)
Affinity DataIC50:  260nMAssay Description:Blockade of human Nav1.7 by voltage ion probe reader based FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325818(2-(2'-(trifluoromethoxy)biphenyl-3-yl)thiazole-4-c...)
Affinity DataIC50:  8.79E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325818(2-(2'-(trifluoromethoxy)biphenyl-3-yl)thiazole-4-c...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50325818(2-(2'-(trifluoromethoxy)biphenyl-3-yl)thiazole-4-c...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed