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Found 3 of ic50 for monomerid = 50394817
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394817(CHEMBL2163832)
Affinity DataIC50:  4nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394817(CHEMBL2163832)
Affinity DataIC50:  12nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394817(CHEMBL2163832)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of human CYP3A4 using testosterone as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed