Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ic50 for monomerid = 50505783
TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at rat luteinizing hormone receptor expressed in rat ovary granulosa GLHR15 cell suspension assessed as reduction in agonist-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLutropin-choriogonadotropic hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50:  185nMAssay Description:Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at holding potential -80 mV by whole-cell voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50: >1.60E+4nMAssay Description:Antagonist activity at human follicle stimulating hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate treated prior to substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Bayer

Curated by ChEMBL
LigandPNGBDBM50505783(CHEMBL4458424)
Affinity DataIC50:  2.40E+4nMAssay Description:Antagonist activity at human thyroid stimulating hormone receptor expressed in rat HTC133 cells assessed as reduction in agonist-induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed