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Found 4 of ic50 for monomerid = 50587164
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50587164(CHEMBL5089882)
Affinity DataIC50:  180nMAssay Description:Inhibition of CYP3A4 (unknown origin) using ketoconazole as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50587164(CHEMBL5089882)
Affinity DataIC50:  950nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50587164(CHEMBL5089882)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50587164(CHEMBL5089882)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using quinidine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed