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Found 11 of ic50 for UniProtKB: P35590
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50: <1.00E+3nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50097956(3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidi...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of TIE1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50092082(CHEMBL3582441)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Tel-fused TIE1 (unknown origin) expressed in mouse BA/F3 cells after 48 hrs by luciferase reporter gene assay in absence of recombinant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50575343(CHEMBL4858720)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of TIE1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50092080(CHEMBL3582427)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Tel-fused TIE1 (unknown origin) expressed in mouse BA/F3 cells after 48 hrs by luciferase reporter gene assay in absence of recombinant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50092081(CHEMBL3582442)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Tel-fused TIE1 (unknown origin) expressed in mouse BA/F3 cells after 48 hrs by luciferase reporter gene assay in absence of recombinant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50092079(CHEMBL3582439)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of Tel-fused TIE1 (unknown origin) expressed in mouse BA/F3 cells after 48 hrs by luciferase reporter gene assay in absence of recombinant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50538508(CHEMBL4634073)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TIE1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50575344(CHEMBL4854822)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of TIE1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50538507(CHEMBL4640601)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of TIE1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50538509(CHEMBL4636995)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of TIE1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed