TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of wild-type HIV1 BH10 protease expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Binding affinity to HIV1 protease assessed as inhibition constant using Val-Ser-Gln-Asn-betaNal-Pro-Ile-Val as substrate by HPLC methodMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Csir-National Chemical Laboratory
Curated by ChEMBL
Csir-National Chemical Laboratory
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.540nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.739nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Inhibition of HIV1 recombinant protease D30N/N88D mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of HIV1 recombinant protease A71V/V82T/I84V mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Inhibition of HIV1 recombinant protease M46I/A71V/V82T/I84V mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibition of HIV1 recombinant protease L10F/L19I/K20R/L33F/E35D/M36I/R41K/F53L/I54V/L63P/H69K/A71V/T74P/I84V/L89M/L90M/I93L mutant expressed in Esch...More data for this Ligand-Target Pair
TargetHIV-1 protease(Human immunodeficiency virus)
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Inhibition of HIV1 recombinant protease V32I/I47A mutant expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair