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Found 5 of ki for monomerid = 50204595
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50204595(CHEMBL3889667 | US10285989, Example 94)
Affinity DataKi:  0.800nMAssay Description:Inhibition of rhesus monkey PDE2A3 expressed in AD293 cells using FAM-labeled cAMP as substrate after 60 mins in presence of cGMP by florescence pola...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50204595(CHEMBL3889667 | US10285989, Example 94)
Affinity DataKi:  0.800nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50204595(CHEMBL3889667 | US10285989, Example 94)
Affinity DataKi:  0.900nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50204595(CHEMBL3889667 | US10285989, Example 94)
Affinity DataKi:  0.960nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50204595(CHEMBL3889667 | US10285989, Example 94)
Affinity DataKi:  1.20nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
In DepthDetails US Patent