TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Baylor College of Medicine
Curated by ChEMBL
Baylor College of Medicine
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Competitive inhibition of recombinant human DOT1L using adenosine/deazaadenosine as substrate and SAM cofactorMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Baylor College of Medicine
Curated by ChEMBL
Baylor College of Medicine
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Inhibition of human recombinant DOT1L catalytic domain amino acid (1 to 472) using [3H]-SAM after 30 mins by scintillation counterMore data for this Ligand-Target Pair